Sildenafil: Commonly known by its brand name Viagra, is a medication primarily used to treat erectile dysfunction (ED) in men. It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors, which work by increasing blood flow to the penis during sexual stimulation. This improved blood circulation helps men achieve and maintain an erection. Sildenafil is usually taken about an hour before sex. It does not need to be taken daily, only as needed.
Tadalafil: Commonly known by its brand name Cialis, is also a PDE5 inhibitor and is used to treat erectile dysfunction. Like sildenafil, tadalafil works by increasing blood flow to the penis during sexual stimulation, helping men achieve and maintain an erection. Tadalafil has a faster onset of action, approximately 30-60 minutes and a longer duration of action, which can last up to 36 hours. Tadalafil can be taken daily or as needed.
Apomorphine: This is a medication that has been used for various medical purposes, including the treatment of erectile dysfunction and Parkinson’s disease. It acts as a dopamine agonist, meaning it stimulates certain dopamine receptors in the brain. In the context of erectile dysfunction, apomorphine can help improve sexual function by increasing blood flow to the penis and enhancing sexual arousal. It is typically administered as a sublingual tablet or as an injection.